"This blog was developed to provide medical updates that are important and have my perspective as additional insight."
Coumadin has had a virtual monopoly as an oral anticoagulant since it was first used in 1940 at Wisconsin General Hospital. Discovered accidentally when scientists investigated hemorrhaging of livestock who ate spoiled sweet clover when grazing, it took a decade to isolate dicoumarol and use it in the clinic. Initially showing success in preventing blood …
Xarelto and Pradaxa and two new anti-coagulant medications that have similar effects to Coumadin (warfarin). Because their mechanism of action is different than Coumadin, they are simpler to use as they do not require blood monitoring. Pradaxa was approved over two years ago and appears to be equally effective to Coumadin for atrial fibrillation, but …
Read More “NEW COUMADIN ALTERNATIVES….RANGE OF USE STILL TO BE IDENTIFIED”
A recent analysis of the new anticoagulants to replace Coumadin (Warfarin) is looking quite favorable when treating blood clots. This is expanding their indication, usage and safety. In the U.S. the two alternatives are PRADAXA and XARELTO, with Xarelto appearing to be somewhat more advantageous with less issues from bleeding. Such alternatives are sorely needed …