Concerns have been raised about high-dose Zocor (80mg) due to concerns about increased risk of interactions with other medications at this dose.
I agree.
There are only a few patients in my practice on this dose and all of them are on it for very specific reasons. High dose Zocor offers little benefit over the 40mg dose but requires a doubling of dosage to get a modest benefit.
If you are concerned about being on the 80mg dose, please contact me to review. Otherwise, stay on it. the lower dosages are much safer and give a wider range for interacting with other medications (less likely to cause an issue.)